About MitoiX

What MitoiX is

MitoiX is a reference site built around a mechanism–intervention–study graph for mitochondrial biology (respiration, mitophagy, biogenesis, mtROS, NAD⁺, cardiolipin) and the interventions that target it. It is deliberately narrow: a small number of landmark interventions and studies, each fully sourced and honestly qualified, rather than a broad advice article. It reports what each study measured, in which population, and at which endpoint. NAD⁺/sirtuin pharmacology overlapping NAD⁺ metabolism is cross-referenced to the mtorix cluster, not duplicated.

The central honesty fact

No mitochondrial intervention has a healthy-aging human lifespan randomized controlled trial. The human evidence here is real but qualified: functional (muscle/vascular), biomarker (NAD⁺, immune), or disease-outcome. CoQ10's mortality benefit (Q-SYMBIO) is in chronic heart-failure patients, not healthy aging; elamipretide's 2025 FDA approval is for the rare disease Barth syndrome, not aging; urolithin A's muscle trials are functional endpoints, not lifespan. Every intervention page carries an evidence flag that reflects this, and no page claims a human longevity effect.

Publisher / editorial identity

Nabus Research is the editorial owner and publisher. This site does not attribute content to any named individual author or reviewer; no person is fabricated for E-E-A-T purposes. When a named, verifiable human reviewer is assigned to a page in a future revision, that attribution will be added — and not before.

Sourcing standard

Every study record carries five visible qualifiers: species/population; exposure, route and schedule; comparator and duration; endpoint and numeric result; and what the study did NOT establish. Every record carries a verification_status, and every trial/registry identifier a citation_status. Journal/volume/DOI were confirmed via Crossref and trial status via the ClinicalTrials.gov v2 API where an identifier was resolvable; where an exact NCT/PMID was not confirmed against the primary record, it is marked needs_primary_fulltext rather than presented as verified — see the methodology page.

Monetization

Monetization is off in v1. No affiliate links, no sponsored placements, no ads.txt. This is a reference resource, not a shopping guide.

Prohibited claim language

The editorial process blocks a fixed list of prohibited phrases (e.g. claims of reversing mitochondrial aging, repairing your mitochondria, or a proven human lifespan effect) via an automated pattern check run at build time. See generators/check_claim_patterns.py.

Licensing & data enquiries

The structured mitochondrial evidence dataset behind this site is independently sourced. For dataset-licensing or research-data enquiries, use the form below. This is an inbound enquiry channel only — no advertising, affiliate links, or sponsored placements appear on this site.

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